decoupler.get_progeny

decoupler.get_progeny(organism='human', top=100)

Pathway RespOnsive GENes for activity inference (PROGENy).

Wrapper to access PROGENy model gene weights. Each pathway is defined with a collection of target genes, each interaction has an associated p-value and weight. The top significant interactions per pathway are returned.

Parameters
organismstr

Which organism to use. Only human and mouse are available.

topint

Number of genes per pathway to return.

Returns
pDataFrame

Dataframe in long format containing target genes for each pathway with their associated weights and p-values.