decoupler.rank_sources_groups

decoupler.rank_sources_groups(adata, groupby, reference='rest', method='t-test_overestim_var')

Rank sources for characterizing groups.

Parameters:

adataAnnData

AnnData obtained after running decoupler.get_acts.

groupby: str

The key of the observations grouping to consider.

reference: str, list

Reference group or list of reference groups to use as reference.

method: str

Statistical method to use for computing differences between groups. Avaliable methods include: {'wilcoxon', 't-test', 't-test_overestim_var'}.

Returns:

results: DataFrame with changes in source activity score between groups.